What are the conditions to be met for the identification of regenerative obstructive anaemia?

Anaemia regenerative (Aplastic Anemia, known as AA) is a blood disease caused by the failure of bone marrow blood function, characterized by a decrease in the whole blood cell, including red cells, white cells and slabs. The diagnosis of regenerative obstructive anaemia requires the following conditions, including clinical performance, laboratory examination and bone marrow puncture work.Clinical performanceClinical manifestations of regenerative obstructive anaemia usually include the following:Symptoms of anaemia: inefficiency, fatigue, pale face, heart attack, difficulty of breathing, etc.Incidence: due to the reduction of white cells, patients are vulnerable to repeated infections and infections are not easily controlled.Haemorrhagic tendencies: due to a decrease in slabs, patients may suffer from skin bruises, bruises, haemorrhage of teeth, haemorrhage of nose and multiple female months.Hepatic, spleen and lymphomy are not swollen: this is an important feature of regenerative obstructive anaemia, distinguished from blood diseases such as leukaemia.Laboratory inspectionLaboratory tests are key to the diagnosis of regenerative obstructive anaemia, and include, inter alia, the following:Routine blood tests: All blood cells are shown to be decreasing, i.e. haemoglobins, red cells, white cells and platelets are below normal values.Bone marrow smears: The bone marrow smears from bone marrow piercing show a low bone marrow growth and a significant decrease in the particle, red and meganucleus cells.osteomymystery: The proportion of blood-forming tissues to fatty tissues is reduced by bone marrow work.Osteo-marrow cell culture: shows reduced capacity to form stem blood cells.Conditions for diagnosisThe diagnosis of regenerative disorders requires the following:Declining whole blood cells: regular blood tests show a decrease in the number of red cells, white cells and slabs, with at least two conditions:Absolute value of neutral particle cells <1.5 x 10^9/LSlate count <100 x 10^9/LHemoglobin < 100g/L (female < 110g/L)Osteo-marrow failure: bone marrow piercing and/or biopsy show at least one part of the bone marrow growing low or extremely low, and non-blood cells (e.g. fat cells) increasing.Exclusion of other diseases: Elimination of other diseases that may lead to a reduction in the whole blood cell, such as tremor sleeping haemoglobinuria (PNH), bone marrow amplification syndrome (MDS), acute leukaemia, systemic erythalamus (SLE) etc.The following is a detailed explanation of these conditions:All blood cells are down.Declining of whole blood cells is a typical manifestation of regenerative obstructive anaemia. Regular blood testing is a necessary step in the initial screening, and the following are usually found:Reduction of erythrocyte: Acemia symptoms.White cell decline: resulting in reduced immunity and vulnerability to infection.Declining platelets: leading to haemorrhage.Bone marrow failure.The bone marrow failure is the core pathological characteristic of regenerative obstructive anaemia. The bone marrow piercing and biopsy are key steps in the diagnosis and are usually found:Bone marrow growth is low: the number of blood cells has decreased and the ratio to fat cells has decreased.Decrease in particle, red and meganucleus cells: The decrease in these three cells is a typical manifestation of regenerative obstructive anaemia.Exclude other diseasesOther diseases that may lead to similar symptoms and laboratory results must be eliminated before regenerative obstructive anaemia is diagnosed. The following diseases need to be eliminated:Synthetic sleeping haemoglobinuria (PNH): Excluded by testing the expression CD55 and CD59 by fluent cytology.Osteo-marrow amplification syndrome (MDS): excluded through bone marrow work and cytogenetic analysis.Acute leukaemia: excluded through bone marrow smears and immune spectrometry.Systemic erythalamus (SLE): excluded through anti-nucleus (ANA) and other self-antibody tests.Integrated assessmentThe diagnosis of regenerative obstructive anaemia requires a comprehensive medical assessment based on the patient ' s clinical performance, the results of laboratory examinations and the process of removing other diseases. In some cases, additional examinations, such as chromosome analysis, genetic tests, etc., may be required to provide further clarity of diagnosis.In summary, the diagnosis of regenerative obstructive anaemia is a complex process that requires a combination of clinical performance, laboratory tests and the elimination of other diseases. Once diagnosed, the patient should be treated as early as possible to improve the prognosis.