What are the signs of an improvement in re-infective anaemia?

Restorative obstructive anaemia (Aplastic Anemia, AA) is a blood disease caused by the failure of bone marrow blood function, which is characterized by a decrease in all blood cells. The treatment of regenerative obstructive anaemia includes immunosuppressive treatment, blood growth factors treatment, bone marrow transplants, etc. The following are some signs of improvement in regenerative obstructive anaemia:1. Improved blood testingIncrease in the total blood count (CBC): this is the most direct sign of improvement. The increase in the number of red cells, white cells and slabs indicates that the blood function of bone marrow is being restored.The increase in the number of weeded red cells: the increase in the number of weeded red cells, which is premature, means that the bone marrow is producing more red cells.Hemoglobin levels have increased: hemoglobin is the protein that carries oxygen in the red cells, and the increase indicates that anaemia is improving.2. Mitigation of clinical symptomsReduced fatigue: As haemoglobin levels rise, patients ‘ sense of fatigue and weakness diminish.Decreased infection: Increased white cell means improved functioning of the immune system, reduced risk and reduced number of infections.Haemorrhage tends to be reduced: the increase in the number of slabs helps to stop the bleeding, so the tendency to haemorrhage (e.g. skin bruises, nose bleeding, tooth bleeding, etc.) is reduced.3. Improvement of bone marrow examinationOsteo-marrow cell increase: Doctors can observe an increase in the number of blood cells in the bone marrow and a decrease in fattening through bone marrow puncture and biopsy.Bone marrow blood graft: In vitro graft, if the growth of blood graft can be observed, this indicates that the bone marrow ‘ s potential is being restored.4. Improvement of immunological indicatorsThe level of self-antibody is decreasing: among some immuno-mediated patients with regenerative disorders, the level of self-antibody is likely to decrease.T-cell function regulation: T-cell sub-group ratio and function can be detected through tests such as current cytology.5. Improved quality of lifeIncreased physical and mobility: As anaemia improves, patients are able to perform more routine activities and physical exercise.The emotional and psychological state of the patient will improve as the physical condition improves.Response to drug treatmentResponse to immunosuppression treatment: Patients receiving immunosuppression treatment show that the treatment is effective if there are signs of improvement in haematology as described above.Reduced reliance on blood transfusions and growth factors: With the restoration of self-made blood function, patients may need less support from blood transfusions and haemogenic factors.7. Signs of stability in long-term follow-up visitsLong-term stabilization of blood cell count: In long-term follow-up visits after treatment, this is an important sign of improvement if the blood cell count remains stable without further decline.There is no evidence of progress: through regular bone marrow examinations and haematological assessments, if there are no signs of progress, such as bone marrow fibrosis or conversion to bone marrow amplification abnormalities (MDS).8. Reactions to blood growth factorsReaction to the treatment of blood growth factors: If the number of blood cells rises after the patient is treated with blood growth factors, this indicates that the bone marrow responds to the treatment.AttentionIndividual differences: The response to treatment may vary from patient to patient, and the signs and speed of improvement may vary.Ongoing monitoring: Even if there are signs of improvement, patients still need regular blood and bone marrow examinations to monitor progress.Integrated assessment: An improved assessment should be based on a comprehensive consideration of multiple examinations and clinical performance, not just changes in a single indicator.Overall, signs of improvement in regenerative obstructive anaemia include improved haematological examinations, reduction of clinical symptoms, improvement of bone marrow examinations, regulation of immunological indicators, improvement of quality of life and effective response to drug treatment. Patients and doctors should work closely together to monitor improvements through regular examinations and assessments.