There is a wide variety of biological agents commonly used in rheumatism immunization, which are targeted at different inflammations and immunosuppressants and are used to treat multiple rheumatological diseases. The following are more than 10 biological agents, their use and possible side effects:
1. Patronic inhibitor (TNF inhibitor) for cancer causes:
Medicines: Enbrel, Humira, Remicade, Simponi, Cimzia.
Treatment of diseases: mainly for direct spinal and rheumatological arthritis.
Sub-reactions: may include injection partial reaction, increased risk of infection, potential for or aggravated heart failure, nervous system problems, etc.
2. White cell media inhibitors:
Drugs: Actemra for IL-6 and Kineret for IL-1.
Treatment of diseases: The beads are used for the treatment of rheumatism arthritis and other inflammatory diseases, and Anabinin is used mainly for the treatment of rheumatitis.
Secondary response: may include increased risk of infection, high cholesterol, gastrointestinal perforation (single resistance).
3. B-cell and T-cell inhibitors:
Medicines: Rituxan for CD 20, Orencia for CD 80/CD 86
Treatment of diseases: Letos is used for the treatment of rheumatism, systematic erythropopus, mainly for rheumatism.
Sub-responses: May include infusion response, increased risk of infection, sexual multi-tread white brain disease (PML, rare). 4. Other biological agents:
Medicines: Single resistance to Bailey (Benlysta, for BLyS).
Treatment of diseases: mainly for systemic red lupus.
Secondary response: may include nausea, diarrhoea, fever, infection, etc.
5. IL-12/23.
Medicine: Ussnus (Stelara). Treatment of diseases: For meso-heavy-heavy silver crumbs.
Reactions: May include injections, upper respiratory infections, headaches, etc.
6. IL-17A Resistants: Drugs: Cosentyx, Taltz.
Treatment of diseases: Medium-to-heavy specky silver crumbs, high-relative spinal disease.
Sub-responses: may include inoculations, infections, inflammatory intestinal diseases, etc.
7. IL-6 inhibitors:
Medicine: Saliru Monovalent (Kevzara).
Treatment of diseases: For rheumatism arthritis.
Secondary response: May include increased risk of infection, abnormal liver function, etc.
8. CD20 suppressants:
Medicine: Arzerra.
Treatment of diseases: mainly for certain types of leukaemia and lymphoma.
Sub-responses: May include infusion response, infection, low C-protein.
9. IL-1 Receptors:
Drugs: Arnabin (Kineret).
Treatment of diseases: For rheumatism arthritis.
Secondary response: May include injection partial reaction, headache, upper respiratory infections, etc.
10. B-cell irritant inhibitor:
Medicines: The Beliyo stand alone (Benlysta).
Treatment of diseases: For systemic red lupus.
Secondary response: may include nausea, diarrhoea, fever, infection, etc.
11. T-cell combination irritant inhibitors:
Drugs: Orencia.
Treatment of diseases: For rheumatism arthritis.
Secondary response: May include headaches, nausea, upper respiratory infections, etc.
In the use of these biological agents, doctors closely monitor patients ‘ reactions and possible side effects. In addition, the use of biological agents should focus on their safety, and before drugs are used to screen nodules, except for active infections and tumours. Resistance to infection may be made more difficult by biological agents inhibiting the immune system. Thus, in the use of these drugs, patients are required to undergo regular health examinations to ensure safe and effective management of the disease.
