What causes the regenerative obstructive anaemia?

What causes the recurrence of obstructive anaemia (Aplastic Anemia, AA) is a blood disease caused by the failure of bone marrow blood function, which is characterized by a decrease in the whole blood cell, including red cells, white cells and slabs. The following are various causes that may lead to the re-emergence of obstructive anaemia:1. Genetic factorsFanconi AnemiaVan Goni anaemia is a genetic bone marrow failure syndrome, usually caused by mutation of genes. Not only are patients at risk of bone marrow failure, they may also develop into acute leukaemia or other cancers.Congenital pure red cell regeneration disorder (Diamond-Blackfan Anemia)This disease usually occurs during infancy, in the form of a decrease in red cell formation, but does not affect white cells or slabs.Immunization factorsSelf-immunological diseasesSome patients ‘ immune systems wrongly attacked their own stem blood cells, resulting in loss of bone marrow blood function.Immunomediate bone marrow inhibition.In some cases, viral infections or other factors may trigger an attack on the bone marrow by the immune system, resulting in blood stem cell damage.Chemical factors and drugsChemical exposureLong-term or large-scale exposure to chemical substances such as benzene, pesticides and pesticides can lead to bone marrow inhibition.Drug responseCertain drugs, such as anti-cancer drugs, anti-eclampsia drugs and sulfamides, can cause bone marrow inhibition and lead to regenerative obstructive anaemia.Physical factorsRadiation exposureHigh doses of ionizing radiation, such as nuclear radiation, can directly damage stem blood cells and cause bone marrow failure.5. Virus infectionsCertain viruses, such as the hepatitis virus, the EB virus, the human microvirus B19 and so on, may be directly infected with stem blood cells or indirectly damage bone marrow through immune reactions.6. Other diseasesPNHPNH is a rare blood disease that can lead to fragile fractures of red cells, with possible bone marrow failure.7. Osteroid syndrome (MDS)MDS is a disease that can cause bone marrow failure, and some patients may develop into regenerative obstructive anaemia.8. Unknown reasonsSTD anaemiaIn many cases, despite comprehensive testing, it is not possible to identify the specific causes of regenerative obstructive anaemia, which is described as a specific form of regenerative disorder.ConclusionsThe causes of regenerative obstructive anaemia range from genetic, immune, chemical, physical and viral infections. In some cases, there may be multiple interactions. Due to the complex causes of regenerative obstructive anaemia, a comprehensive assessment by haematologists is required for diagnosis and treatment. In the case of suspected cases, comprehensive examinations, including bone marrow piercing, genetic tests and immunological assessments, should be conducted to determine the causes of the disease and to develop appropriate treatment programmes.