Reconstructive anaemia (Aplastic Anemia, AA) is a blood disease caused by the functional impairment of the bone marrow, which is characterized by a decrease in the whole blood cell, including red cells, white cells and slabs. For persons with regenerative obstructive anaemia, the “basic cure” is a relative concept, which means that the patient’s condition is effectively controlled, his or her blood is restored, the quality of life is significantly improved and does not recur for a certain period of time.Review of diagnostic criteriaBefore discussing “basic cure”, we need to review the diagnostic criteria for regenerative obstructive anaemia, which usually include:Sustained reductions in all blood cells.The bone marrow is low, fattening.Exclude other diseases that cause a reduction in the whole blood cell.Definition of “basic healing”The “basic cure” for regenerative obstructive anaemia usually meets the following conditions:Clinical symptoms and signsAnemia is reduced: the patient is no longer suffering from apparent infirmity, heart palpitation, gas shortness, etc.Incidence and haemorrhage: Patients are no longer frequently affected by infection and haemorrhage, or their frequency and severity are significantly reduced.No blood transfusion: Patients can maintain sufficient haemoglobin levels without regular blood transfusions.Laboratory inspectionBlood routine: The red cell, white cell and slab count returns to normal or near normal levels.Bone marrow: The growth of the bone marrow has returned to normal, fattening has decreased significantly and the proportion of blood cells in the trilineal line is normal.Osteomystosis: The results of the biopsy suggest that the structure of bone marrow blood is normal.Treatment responseTreatment is effective: patients respond well to treatments such as immunosuppression treatment, blood growth factor treatment or bone marrow transplant.Long-term relief: the patient remains stable and no signs of recurrence after the cessation of treatment.Specific indicatorsThe following are specific indicators for assessing whether persons with regenerative obstructive anaemia have met the “basic cure”:Blood protocol.Hemoglobin: Male 120g/L, Female 110g/L.White cell: ≥3.5×10^9/L.Slabs: ≥50×10^9/L.The bone marrow.Incidence: the increase is clearly active or active.Fatty cells: < 50%.Post-treatment follow-upNo recurrence: within at least one to two years after the cessation of treatment, the patient ' s condition is stable and no signs of recurrence.Quality of life: Patients can return to normal life and work and the quality of life has improved significantly.AttentionIndividual differences: Each patient's condition and treatment response vary, so the definition of “basic healing” may need to be adjusted to individual circumstances.Long-term follow-up: even if the patient meets the standard of “basic cure”, a long-term follow-up is required, as there is a risk of re-emergence of obstructive anaemia.Integrated assessment: Assessment of “basic healing” should take into account clinical symptoms, laboratory findings and therapeutic responses.ConclusionsThe “basic cure” for regenerative obstructive anaemia is a multi-faceted assessment process involving the mitigation of clinical symptoms, the improvement of laboratory results and long-term follow-up after treatment. Although there is currently no cure for regenerative obstructive anaemia, through reasonable treatment and careful observation, many patients have been able to reach a “basic cure”, thus significantly improving their quality of life and life expectancy. For patients, following medical instructions, regular review and timely management of complications are key to maintaining a “basic healing” state.
Posted inHealth and wellness