What is the link between bone marrow amplification syndrome and anaemia?

What is the link between bone marrow amplification syndrome and anaemia? Mylodysplastic Syndromes, MDS, a group of cloned blood diseases originating from blood stem cells, characterized by abnormal bone marrow function, a decrease in outside blood cells, and an increase in the risk of development into acute medular leukaemia. Anaemia is one of the most common clinical manifestations of MDS, with the following links:I. Causes and morbidity mechanismsAnemia due to osteomosis syndromeThe causes of MDS are not yet fully clear, but studies have shown that genetic factors, environmental factors, immunosuppressions, etc. may cause mutations in blood stem cell genes, hindering the process of blood cell separation and maturation in the bone marrow and leading to ineffectual blood production. This ineffectual blood is reduced in red cell formation, leading to anaemia.Anaemia exacerbates musculosis syndromeAnemia can lead to a lack of oxygen in the organ ‘ s tissue, which in turn stimulates the growth of bone marrow and increases the MDS condition. In addition, anaemia can lead to disorders such as inactivity, heart palpitation and gas shortness, which seriously affect the quality of life.II. Clinical performanceAnaemia symptomsMDS patients are often shown to be sexually anaemic, including inactivity, dizziness, heart palpitation and short air. The extent of anaemia is related to the type and severity of the MDS.Other MDS symptomsIn addition to anaemia, MDS patients may have the following symptoms:(1) Haemorrhage: due to the decrease in the platelets, patients are prone to skin bruising and haemorrhage.(2) Infection: The reduction of white cells results in reduced resistance and vulnerability to infection.(3) Hepatic, spleen, lymphine swollen: Some patients can have liver, spleen mildly swollen, and lymphine swollen is less common.Diagnosis and identificationDiagnosisThe MDS diagnosis is based on three main elements:(1) Clinical performance: including symptoms of anaemia, haemorrhaging, infection, etc.(2) Elephant: Decrease in the number of triple blood cells in the outer circle, especially red cells.(3) The bone marrow: The bone marrow amplification is abnormal and pathological blood is visible.Identification diagnosisThe causes of anaemia are numerous, and MDS needs to identify anaemia caused by other causes, such as iron deficiency anaemia, cytocell anaemia and regenerative obstructive anaemia.IV. Therapeutic and prognosisTreatmentThe goal of MDS treatment is to alleviate symptoms, improve the quality of life and reduce the risk of leukaemia conversion. Treatment includes:(1) Support for treatment: blood transfusion, anti-infection, stop bleeding, etc.(ii) Immuno-modified treatment: e.g., use of shalidomide, cyclothylene, etc.(3) Chemotherapy: applies to high-risk MDS patients, such as the use of the Azads, the Catalina, etc.(4) Blood stem cell transplant: applicable to young patients with suitable supplies.AdvanceThe MDS forward is related to the severity of the condition, age of the patient, complications, etc. Some of the patients can be converted to acute marrow leukaemia, with poor prognosis.In general, there is a close link between osteomosis syndrome and anaemia. Ineffective blood production by MDS is the main cause of anaemia, which in turn exacerbates the MDS condition. Therefore, when treating MDS, active interventions should be made to improve the quality of life of patients with anaemia. At the same time, regular follow-up visits are made to patients to detect changes in the situation in a timely manner and to develop appropriate treatment programmes.