What’s all this genetic blood disease?

Genetic blood diseases are a group of diseases of the blood system caused by genetic factors, which usually involve components of the blood or abnormal functions. The following are common genetic blood diseases:1. Mediterranean anaemiathalassaemia is a group of hereditary anaemia due to haemoglobin synthesis abnormalities. It is divided into two main types of α-Malassaemia and β-Malassaemia.α-Malassaemia: Due to genetic defects in the α-Yalpha protein chain, the synthesis of the α-Yalpha protein chain has been reduced, thus affecting the synthesis of haemoglobin.Beta-thalphaemia: Due to genetic defects in the beta-ball protein chain, the combination of beta-ball protein is reduced, which affects the synthesis of haemoglobin.Genetic spherical cell amplificationIt is a genetic disease caused by membrane protein defects, which sphericalizes the red cells and makes them susceptible to destruction in the spleen, leading to soluble anaemia.3. Genetic elliptical cell amplificationIt is a disease caused by membrane protein defects in red cells, which are elliptical and may be damaged in the spleen and cause anaemia.4. Genetic haemorrhagic fine vascular expansionIt is a disease of abnormal vascular development, with potential for abdominal expansion of the patient, leading to repeated haemorrhage, particularly in the nose and gastrointestinal tract.HemophiliaHemophilia is a group of hereditary haemorrhagic diseases due to lack of coagulation factors, mainly haemophilia A (lack of coagulation VIII) and haemophilia B (lack of coagulation IX).6. Von Villebrand ‘ s diseaseThis is a genetic haemorrhagic disease due to a deficiency or abnormal function of an vascular hemophiliasis (VWF), which affects the blood condensation process.7. Genetic plate function abnormalSuch diseases include various haemorrhagic diseases caused by abnormally functioning slabs, such as slab infirmity, slab disease, etc.8. Genetic bone marrow failure syndromeSuch diseases include Vanconi anaemia, congenital pure red cell regeneration disorders, etc., which affect the blood function of bone marrow.9. Geneticly soluble anaemiaIn addition to genetic spherical cell amplification and genetic elliptic cell amplification, there are glucose-6-phosphate dehydrogenase deficiency (G6PD) and acetone acidase deficiency.10. Genetic bone marrow amplification diseasesSuch diseases include chronic medular leukemia (CML), genuine red cell amplification, primary slab amplification, etc.11. Genetic marrow tumoursLike family marrow leukemia.12. Genetic immune deficiency diseasesAlthough these diseases mainly affect the immune system, they can also lead to blood system anomalies, such as Wiskott-Aldrich syndrome, DiGeorge syndrome, etc.Concluding remarksThere is a wide variety of genetic blood diseases, each with its specific genetic patterns and clinical manifestations. Treatment and management of these diseases require assessment and guidance from a professional medical team. As genetic research deepens, genetic diagnostics and treatments for many genetic blood diseases are developing and improving, providing patients with better treatment options and quality of life. For individuals with family history, genetic counselling and testing are important to help them understand the risks of disease and take appropriate preventive measures.