What’s the reason for the decrease in neutral particle cells?

Moderate particle-cell reduction, also known as meso-particle-cell deficiency, means that the number of meso-particle cells in the blood is below normal. Moderate particle cells are a form of white cells, which play a vital role in the human immune system, especially against bacterial and fungi infections. The reduction of neutral particle cells can increase the risk of infection and even threaten life when it is serious. The following is a detailed explanation of the possible causes of the decrease in the number of neutral particles.1. Reduction in generationGenetic diseasesCongenital mesocyte reduction: e.g. cyclical mesocyte reduction, Schwachman-Diamond syndrome, etc., these diseases are usually associated with genetic mutation, resulting in the failure of the bone marrow to produce sufficient mesogenic particles.Bone marrow inhibitionDrug inducing: Certain medicines, especially anti-cancer drugs, anti-eclampsia drugs and some antibiotics, can inhibit the production of neutral particles from bone marrow.Chemical exposure: Long-term exposure to certain chemical substances, such as benzene and other organic solvents, may also lead to a decrease in neutral particle cell formation.Rehabilitation: Radiotherapy, especially for the chest or pelvis, can damage bone marrow and reduce the production of moderately pelvis.Virus infectionViral diseases: viral infections such as hepatitis, HIV and influenza can directly damage bone marrow or indirectly affect the formation of neutral particle cells.Nutritional deficienciesMalnutrition: Lack of nutrients such as vitamin B12, folic acid, iron and copper leads to a decrease in the production of neutral particles.Malignant blood diseaseLeukemia: e.g. acute marrow leukaemia (AML) is an excessive increase in leukemia cells in the bone marrow, inhibiting the production of normal neutral particles.MDS: These diseases affect bone marrow function and result in reduced blood cell formation.Self-immunological diseasesDecline in self-immuno-neutral particle cells: The immune system wrongly attacked its own meso-particle cells, resulting in a decrease in their number.2. Increased destruction or consumptionImmunization WizardSelf-immuno-immunological diseases such as systemic erythalamus (SLE), rheumatitis, etc., and immune system attacks on neutral particle cells.Immuno-blood diseases: e.g. immuno-crombacytopenia (ITP) is accompanied by a reduction in the number of neutral particles.InfectionCertain viral infections, such as infectious mononucleotosis, viral hepatitis and so on, may lead to the destruction of neutral particle cells.GeneticFamily neutron particle cell syndrome: These genetic diseases lead to the premature destruction of neutral particle cells by the immune system.3. Dispersion anomaliesSpleen surge.Spleen spleen spleen: Spleen overcapacitate and destroy neutral particle cells, which are common in cirrhosis of the liver, certain blood diseases and spleen hyperactivity.Other reasonsChronic diseasesChronic inflammation: e.g. inflammation of the intestine, chronic kidney disease, etc., may lead to a decrease in the number of moderately particle cells.StressSerious stress: severe trauma, surgery, burns, etc., can lead to temporary reduction of neutral particle cells.Hormones abnormal.Endocrine diseases, such as thyroid hyperactivity or decline, may affect the production and functioning of neutral particles.Diagnosis and assessmentThe diagnosis of the reduction of neutral particles usually involves the following steps:Detailed medical history inquiries: knowledge of patients ‘ history of drug use, chronic diseases, infections, family history, etc.Medical examination: examination of signs of spleen or other potential diseases.Blood examination: The whole blood cell count (CBC) is the cornerstone of the initial diagnosis, and other examinations may include bone marrow work, cytogenetics, immunology studies, etc.Screening for infection: remove possible causes of infection.Treatment and preventionThe key to the treatment of moderate particle cell reduction is:Demobilisation: Demobilisation of drugs leading to the reduction of neutral particles, treatment of infections, correction of malnutrition, etc.Supportive treatment: Antibiotics may be needed to prevent infection in patients with severe neutral particle cell reductions.Drug treatment: The use of a drug such as a particle-celled irritation factor (G-CSFs) to stimulate the production of moderately particle cells.Immunosuppressive treatment: Immunosuppressants may be needed in the face of a reduction in the number of self-immunosuppressively neutral particles.Preventive measures include:Avoiding known risk factors: e.g., avoiding the use of drugs that may cause the reduction of neutral particles.Periodical screening: periodic blood tests are conducted for populations with a risk reduction of neutral particle cells.The reduction of neutral particle cells is a complex clinical problem that requires a combination of factors for diagnosis and treatment. Timely diagnosis and treatment are essential to prevent infection and improve the quality of life of patients.