Plasma disease, also known as Behchet disease, is a chronic, re-emerging, multisystemal inflammation disease. Its name originates from the Turkish dermatologist Hulusi Behçet, who was first reported in 1937. The disease, which has a high incidence in countries along the ancient Silk Road, is also referred to as “spiritual disease”.
The main clinical manifestations of white sepsis are oral ulcer, genital ulcer, eye inflammation and skin damage, as well as a combination of vascular, nervous, digestive, joint, lung and kidney systems. Oral ulcer is the most common symptom, most of which is the first manifestation of which occurs when the ulcer is clearly in pain, can be single or multiple, can vary in size and depth, can occur in any part of the mouth, such as lips, tongues, cheek mucous membranes, teeth, etc., and can easily be repeated. The genital ulcer is similar to the oral ulcer, but the incidence is relatively low, usually in the vagina, cysts, penises, anal weeks, etc., where the ulcer is often healed. Eye inflammation is also one of the important features of white slug disease, which can be seen in the form of grapes, retina vasculars, corrals, etc., and can lead to loss of sight or even blindness in serious cases. Skin damage is more diverse, with common corrosive red spots, scabies rashes, cystitis, shallow embolisms of veins, and so on, most of which are found in the lower limbs, in the form of red painful knots.
In addition to the above-mentioned common symptoms, there can be anaesthesia and sepsis of an artery and sepsis when pulmonary artery causes high pressure; different symptoms of headaches, dizziness, paraplegia, loss of speech, sensory disorders, mental abnormalities can occur when the nervous system is exhausted, known as neurological palaeatry, which tends to be severe and low aftercare; digestive tracts can be manifested in abdominal pain, diarrhoea, nausea, vomiting, excretion, etc., and serious intestinal ulcer ulcer can lead to piercing, fistula formation; and cosmorosis is dominated by large joints, such as knee and ankles, which manifest themselves as joint pain, swelling and limited activity, but generally do not cause arthrosis.
The causes and the mechanisms for the incidence of pelican disease are not yet clear and are now considered to be related to a variety of factors, including genetic, infectious and immune anomalies. Studies have shown that albinism has a certain genetic orientation and that certain genes may be associated with disease susceptibility. In terms of infection factors, microbial infections, such as viruses and bacteria, can trigger the immune response of the organism and lead to immunosuppressive disorders. In the case of immunopathy, there are a number of abnormally active self-antibodies and immunocellular cells in the patient, and inflammation of inflammatory cell factors occurs, causing inflammation in the vascular wall and tissue of the whole system.
The diagnosis of pelican disease is based primarily on clinical symptoms, while other similar diseases need to be excluded. Diagnostics often need to be considered in a comprehensive manner because of the diversity of their symptoms and the lack of specific laboratory testing indicators. The diagnostic standard currently used is the International Standard for Diagnosis of White Slugs, i.e. the presence of repeated oral ulcer, plus any of the following two: genital ulcer, eye inflammation, skin damage or needle-strangling test positive (an approximately 0.5 cm slashed in the middle of the forearm with an sterile needle No. 20, observed 24 – 48 hours later, and a small red spot of >2 mm in diameter or a herpes to be positive).
The treatment of pediatric disease is based on drug treatment and is aimed at controlling symptoms, reducing relapses and combating major organ damage. For oral ulcer and genital ulcer, a combination of sugar-coated hormonal ointment, oral ulcers, etc., can be used in part to promote healing and pain relief; eye disease patients require specialist eye treatment, which can control inflammation, e.g., scabies, glucose hormonal osteoporosis or eye ointment, immunosuppressants, etc., to prevent visual damage; and skin damage can be based on different types of drug, such as sugar-coated hormonal, salidamid, etc. Immunosuppressants, such as cyclophosphalamide, sulfur, ammonium butterflies, etc., are often applied to patients who are more seriously ill or suffering from significant organs to reduce inflammation. Inflammation can also be quickly controlled during acute onset with the short-term use of sugar cortex hormonal shocks. In addition, biological agents such as tumour cause of death – alpha inhibitors – have been gradually applied in recent years to the treatment of albinism, with better results.
Plasma disease is a chronic disease with long duration and prone to recurrence, requiring long-term follow-up and regular treatment. In their daily lives, patients should be careful to maintain good habits, avoid fatigue and stress, prevent infection, properly exercise physical exercise and improve their health, in order to improve their quality of life and minimize the physical and life effects of diseases. At the same time, because of the multiplicity of systems available for pedestal disease, multidisciplinary and collaborative treatment is also important for improving the prognosis of patients.
