1. Relationship
between breast cancer and estrogen
Estrogen receptor abnormalities: Estrogen receptors are present in breast cancer cells, and these receptors may be abnormally sensitive to estrogen stimulation. When estrogen binds to these receptors, it promotes the proliferation and division of breast cancer cells, which accelerates the growth of tumors. Effects of estrogen exposure: Long-term estrogen exposure may cause DNA damage in breast cells and increase the incidence of breast cancer.
2. Inhibiting the role of estrogen in the treatment of breast cancer and controlling the proliferation of cancer cells: By inhibiting the production of estrogen and reducing the level of estrogen, the proliferation and spread of breast cancer cells can be effectively controlled, which is one of the important strategies for the treatment of breast cancer. Application of anti-estrogen drugs: Some anti-estrogen drugs, such as tamoxifen and letrozole, can combine with estrogen receptors to prevent the combination and action of estrogen, thus achieving the effect of inhibiting breast cancer growth.
3. Complicated application of estrogen in breast cancer treatment Postoperative adjuvant therapy: After breast cancer surgery, in order to establish an artificial cycle, avoid withdrawal bleeding and prevent recurrence of breast cancer, it is sometimes necessary to supplement estrogen appropriately under the guidance of doctors. But this does not mean increasing estrogen levels, but by regulating hormone balance to achieve therapeutic effect.
Individualized treatment strategy: The use of estrogen in the treatment of breast cancer needs to be individually adjusted according to the specific situation of patients. For example, premenopausal and postmenopausal breast cancer patients may require different treatment options.
4. Other considerations for breast cancer treatment Comprehensive treatment: The treatment of breast cancer is usually based on surgery, including radiotherapy, chemotherapy, endocrine therapy and other means. Suppressing estrogen is only one part of the equation, and it needs to be combined with other treatments.
Lifestyle adjustments: In addition to medication, breast cancer patients also need to pay attention to lifestyle adjustments, such as reducing red meat intake, increasing fish intake, and maintaining a healthy weight, which can help reduce estrogen levels and reduce the risk of breast cancer recurrence.
To sum up, the reason why estrogen is inhibited in breast cancer treatment is that estrogen is closely related to the proliferation and diffusion of breast cancer cells. By inhibiting the production of estrogen and reducing estrogen levels, breast cancer growth can be effectively controlled. However, in the actual treatment, the application of estrogen also needs to be individualized according to the specific situation of patients, and combined with other treatment methods.
Breast cancer
